Das LOGIC-Projekt - Präventive und Rehabilitative Sportmedizin, München - Klinikum Schönsicht, Berchtesgaden
Exercise and Cancer Sport und Krebs 2011

LOGIC-trial // Welcome

Long-term effects of lifestyle intervention in Obesity and Genetic Influence in Children


The aim of the LOGIC trial (Long-term effects of Lifestyle intervention and Genetic Influence in Children) is to investigate the short-, middle-, and long-term associations between body weight (loss) and polymorphisms in adiposity relevant genes, cardio-metabolic parameters, lifestyle and quality of life. The trial runs since January 2006 and up to the end of 2013 nearly 1.500 children could be included.


Participants are 8 to 19 year old children and adolescents with overweight or obesity, who started a standardized in-patient weight loss therapy that focuses on a calorie restricted diet, adequate physical activity and behavior therapy at the rehabilitation center Klinik Schönsicht, Berchtesgaden, Germany.


The study is separated into two main parts:

In-patient therapy

Participants were recruited on their arrival day at the rehabilitation center. Blood samples and anthropometrical measurements weretaken and questionnaires on physical activity, dietary intake and/or quality of life werecompleted at the beginning and the end of the therapy (after 4 to 6 weeks).


Follow-up measurements took place 6 months, 1 year, 2 years, 5 years and 10 years after the in-patient therapy. Participants once more completed the study questionnaires and visited their general practitioner for examination of anthropometry, blood pressure and Tanner status. At the 5 year and 10 year follow-up examination blood parameters were collected to analyze cardiometabolic risk parameters, inflammation markers and adipokines.


This work is supported by the Else Kröner-Fresenius-Stiftung and the Rentenversicherung Bayern Süd and the German Center for Cardiovascular Research, partner site Munich Heart Alliance.



Congress articles

Information drucken

Supporting societies

Klinik Schönsicht Berchtesgaden
Die Else Kröner-Fresenius-Stiftung
Die Deutsche Rentenversicherung Bayern Süd
© Projektleitung "LOGIC-Studie"